This is the first report describing the antibacterial and acetylcholinesterase inhibitory activities of S. crispus on the basis of the isolated constituents.

1. Medicinal Properties of Strobilanthes crispus: A Review Cheng HP, et al., BAOJ Pharm Sci 2015, 1:2 1: 007 . 10:422010. . Strobilanthes crispus (Acanthaceae) has been used traditionally as antidiabetic, diuretic, antilytic, and laxative and has been proven scientifically to possess high antioxidant activity, anti-AIDS, and anticancer properties. The objective of the study was to evaluate the effect of a dietary herbal mix comprised of Vitex trifolia (VTE), Strobilanthes crispus (SCE) and Aloe vera (AVE) on the growth performance, disease resistance and histology of Oreochromis sp. The flowering plant species of the world have been estimated to be about 422,000. The leaves are the part that is often used as the herbal products such as; herbs, tea and the others. Bioactive sub-fractions from the tropical herbal plant Strobilanthes crispus (S. crispus) has been shown to induce apoptosis of breast cancer cells in vitro and reduce tumor size in vivo by our earlier studies. However, long term administration of NSAIDs leads to various complications. Studies had shown that medicinal benefits of Centella asiatica L., Curcuma longa L., and Strobilanthes crispus L. (Somchit et al., 2004, 2005; Wang et al., 2010) highlighted the urgent need for analytical techniques to determine and identify their active compounds. The leaves are used traditionally for treatment of cancer and diabetes, usually taken as a tea or infusion of the leaves.

Strobilanthes crispa Blume is a plant native to countries including Madagascar and Indonesia. Objective: This study aims to determine the . Strobilanthes crispus is traditionally used as a folklore medicinal plant in Malaysia and Indonesia as an antidiabetic, diuretic, or antilithic agent as well as a laxative to treat constipation . Maintain kidney health the kidney is a very important organ in the body.

Used for both culinary and medicinal purposes in India and China. Strobilanthes crispus ZII 109 (L) Bremek or Saricocalix crispus ZII 109 (L) Bremek (Acanthaceae) plant is a native to countries from Madagascar to Indonesia,3 and was first quoted by Anderson. A number of studies demonstrated that S. crispus crude extracts are cytotoxic to cancer cell lines.

Types of diseases that can be treated using medicinal plants include diabetes mellitus, . 1.1 The Usage of Medicinal Plants 1 1.2 Strobilanthes crispus Plant 3 1.2.1 Botanical Description 3 1.2.2 Biological Activity 5 1.2.3 Phytochemistry 5 1.3 Sonchus arvensis Plant 7 1.3.1 Botanical Description 7 1.3.2 Biological Activity 8 1.3.3 Phytochemistry 9 1.4 Analysis and Isolation of the Chemical Constituents 10 Strobilanthes crispus or locally known as Pecah Kaca among Malaysian is a medicinal plant that belongs to the family Acanthaceae. Over the past decades, there has been a rising trend in the prevalence of non-communicable diseases and their risk factors in Malaysia. The pharmacotherapeutic properties of S. crispus tea on Besides that, medicinal plants also . Thus, this present study was conducted . Malaysia is a megadiverse country with a high number of endemic vascular plant .

We investigated the anticancer activities of a native plant, Strobilanthes crispus, valued for its traditional medicinal use. Abstract. Herein, this paper reviews the anticancer properties of S. crispus, providing information for future research and further exploration. Crude extracts of this plant have been found to be cytotoxic to human cancer cell lines and protective against . Antiproliferative properties and antioxidant activity of various types of Strobilanthes crispus tea. The use of medicinal plants is broad enough to treat several types of diseases therapeutically[1]. Thomas classified the It is known as pokok pecah kaca or pokok pecah beling in Malaysia, and pecah beling, enyoh kilo, kecibeling or kejibeling in Indonesia. Strobilanthes cripus was able to reduce cell viability and proliferation in MTT and BrdU assays.Both cell cycle progression and Tunel assay suggested that IC 50 of S. crispus ethanol extract induced sub-G1 cell cycle phase, and DNA fragmentation. S. crispus, classified under the Family of Acanthaceae and locally known as 'daun pecah kaca' or 'jin batu' is a type of . It is commonly consumed in the form of herbal tea. On the other hand, translocation of mitochondria cytochrome c release, induction of caspase 3/7 and p53 while suppress XIAP on treated MCF-7 .

Abstract. Phytosterols, that can be found in Keji Beling (Strobilanthes crispus.) It is commonly consumed in the form of herbal tea. Strobilanthes crispus is traditionally used as a folklore medicinal plant in Malaysia and Indonesia as an antidiabetic, diuretic, or antilithic agent as well as a laxative to treat constipation [ 3 ]. One of the herbs that have great potential is Strobianthes crispus. other medicinal plants that exhibiting anti-inflammatory property. KW - Drying. BMC Complement Altern Med. New research examined several plants that people have used to treat cancer since ancient times. Strobilanthes. Back to Top Where Found The Black Face General plant is native to Malaysia, Indonesia and Madagascar. The involvement of the glycolysis pathway in producing these effects is unconfirmed, thus further investigation is required to elucidate this phenomenon. Acanthaceae ( Strobilanthes crispus) with the common name of "pokok pecah beling" is a native plant to Madagascar, Indonesia, and Malaysia. BAOJ Pharm Sci 1: 007. Int J Cancer Res. One of them is a flavonoid-containing medicinal plants, Strobilanthes crispus which has been traditionally claimed to possess anti-inflammatory and antioxidant . Destroying gallstones The presence of gallstones will disrupt the performance of bile as neutralizing toxins. Keji Beling (Strobilanthes crispus L.) is one of medicinal plants in Acanthaceae family. This study was aimed to evaluate the effect of Strobilanthes crispus extract for possible protection against lipid peroxidation and DNA damage induced by iron nitrilotriacetate (Fe-NTA) and hydrogen peroxide (H2O2). Snake Bite Tumors Action of Strobilanthes Crispus Most Effective Anticancer Antioxidant Cytotoxic Highly Effective Antidiabetic Effective Antimicrobial Diuretic The results indicated that S. crispus oral administration significantly inhibited colorectal carcinogenesis induced by AOM as revealed by the reduction in the number of ACF. Background: Survival and progression of cancer cells are highly dependent on aerobic glycolysis. KW - Strobilanthes Crispus Strobilanthes crispus is a bush-like plant, found mostly in tropical countries ranging from Madagascar to Indonesia on riverbanks or abandoned fields [1]. Objective: This study aims to determine the . Overcoming Respiratory Tract Inflammation. The plant possesses high vitamin and mineral content as well as phytochemicalslike phenols, catechins, tannins, and flavonoidsthat are known to have therapeutic effects. The plant is also known as Hei Mian Jiang Jun (Black-faced General) to the local Chinese community and the leaves of the plants are normally boiled . Results and Discussion A total of 132 extracts obtained from 21 plant species were subjected to the antiviral .

Strobilanthes crispus has been shown to have promising anticancer effects on breast cancer cells. MAHD and HD methods have been compared and evaluated for their performance in the isolation of essentials oil from Strobilanthes Crispus leaves. The C. asiatica L. is an ayurvedic medicine and different uses Anticancer activity of a sub-fraction of dichloromethane extract of Strobilanthes crispus on human breast and prostate cancer cells in vitro. Andrographis paniculata and Strobilanthes crispus are two medicinal plants from Acanthaceae family, known to have antidiabetic activity.This study aimed to investigate the molecular interaction of A. paniculata and S. crispus phytochemical constituents with various macromolecular targets of antidiabetic agent through molecular docking. Strobilanthes crispus or locally known as Pecah Kaca among Malaysian is a medicinal plant that belongs to the family Acanthaceae. The biochemical properties of S. crispus show the potential for anti-obesity treatment. Journal of Medicinal Plants Research, 5(16), 3660-3666. The use of medicinal plants has been extensively investigated for several years. Results. We showed that a bioactive sub-fraction of S. crispus leaves (SCS) induced cell cycle arrest and apoptosis of human . Strobilanthes crispus is one of the most commonly used traditional medicines from Madagascar to Malaysia. The plant possesses high vitamin and mineral content as well as phytochemicalslike phenols, catechins, tannins, and flavonoidsthat are known to have therapeutic effects. activities of S. crispus on the basis of the isolated constituents. Four . S. crispus was analyzed for DPPH free radical scavenging, nitric oxide (NO) and ferric acid reduction. This study aims to determine the characteristics of the functional groups of organic compounds, mineral content and antioxidant activity in the leaf . This study was conducted to study the phenolics content and antioxidant properties of S. crispus leaf as affected by . 11. The plants contained high amount of mineral content and vitamin C, B1 and B2. Strobilanthes crispus (Acanthaceae) has been used traditionally as antidiabetic, diuretic, antilytic, and laxative and has been proven scientifically to possess high antioxidant activity, anti-AIDS, and anticancer properties. Keywords . The Strobilanthes crispus ZII 109 (L.) Bremek or Saricocalyx crispus ZII 109 (L.) Bremek (Acanthaceae) plant is native to countries from Madagascar to Indonesia, and is commonly known as "daun picah crispus Blume. Batu Jin (Malay) Daun Batu Karang (Malay) Keji Beling (Malay) Lidah Jin (Malay) Strobilanthes crispus ( S. crispus) is a herbal medicinal plant that is indigenous in Madagascar and the Malay Archipelago. Strobilanthes crispus S. crispus) is a herbal medicinal plant that is indigenous in Madagascar and the Malay Archipelago. Background: Survival and progression of cancer cells are highly dependent on aerobic glycolysis.

-Consumption of the leafy extract daily as an herbal tea could contribute to the additional nutrients and antioxidants needed in the body to enchance the defense system,especially toward the incidence of degenerative diseases. Strobilanthes crispus, valued for its traditional medicinal use. is very little record of this plant being used for medicinal purposes, a study in Indonesia found that an infusion of the dried leaves of Strobilanthes crispus (S. crispus) has been used as anti-diabetic, diuretic, antilytic, and laxative (12). Use sharp pruners to snip a 3-inch cutting from a healthy stem, making the cut just below a node. Its leaves have been traditionally used to treat various ailments including breast and uterine cancers and gastrointestinal and kidney diseases [ 6, 7 ]. S. crispus has demonstrated multiple anticancer therapeutic potential in vitro and in vivo. This plant are used in medicinal and to treat a variety of ailments in the various traditional systems of medicine. The plant's flowers are yellow. Furthermore, S. crispa has potential in treating cancer, as evidenced in previous studies. This research work has provided scientific proof of the traditional medicinal use of the leaves of S. crispus.

The plant possesses high vitamin and mineral content as well as phytochemicalslike phenols, catechins, tannins, and flavonoidsthat are known to have therapeutic effects.

References ^ a b "Strobilanthes crispa". This study was conducted to study the phenolics content and antioxidant properties of S. crispus leaf as affected by . FU inhibits thymidylate synthase (TS) and is incorporated into the RNA and DNA.

To help overcome health problems such as inflammation of the respiratory tract, we can also utilize the content of the Magnolia flowers to help overcome the disorder.

The mechanism involves "Medicinal plants have been used for the treatment of diverse . According to a study in 2014, extracts of three ancient Ayurvedic herbs namely Curcuma longa L., gotu kola (Centella asiatica) and Strobilanthes crispus L. were used to treat the herpes virus. One of them is Kejibeling (Strobilanthes crispus). for . The Strobilanthes crispus plants were purchased from herbal supplier in Kota Kinabalu and were verified by a botanist from Tropical Biology and Conservation Institute, University Malaysia Sabah . Its leaves are commonly used in preparation of infusion to prevent diabetes and have diuretic, antilytic, and laxative effects. BMC Complement Altern Med. . Numerous naturally-occurring compounds have been proposed as treatment for weight The plant is Keywords Strobilanthes crispus Adipose tissue Lipolysis Leptin Article history Received: 22 July 2015 Received in revised form: A number of studies demonstrated that S. crispus crude extracts are cytotoxic to cancer cell lines. The effect of microwave power, extraction time and water to raw material ratio . S. crispus has been used as traditional medicine for its antidiabetic, diuretic, anticancer and blood pressure lowering properties [2]. Strobilanthes crispus ( S. crispus) is a herbal medicinal plant that is indigenous in Madagascar and the Malay Archipelago. Species. View Article: Google Scholar. Some common and very useful Anticancer herb plants example like "Black Face General" - Hei Mian Jiang Jin (Strobilanthes Crispus), "Yu Xun Cao" , (Sabah Snake Grass, Clincanthus Nutans), "Huo Tan Mu" (Smartweed), Qi Xin Chen (Pereskia Sacharosa) and it is grown in Malaysia and many other Asia countries as for anti-cancer herb plants. These medicinal plants are Bandicoot Berry (Leea indica), Sabah Snake Grass (Clinacanthus nutans), Fool's Curry Leaf (Clausena lansium), Seven Star Needle (Pereskia bleo), Black Face General (Strobilanthes crispus), South African Leaf (Vernonia amygdalina), and Simpleleaf Chastetree (Vitex trifolia).

Strobilanthes Crispus Cures Most Effective Breast Cancer Colon Cancer Liver Cancer Highly Effective Diabetes Kidney Stones Effective Bladder Stones Diarrhea Hepatitis C High Cholest.

Back to Top Medicinal Properties Strobilanthes crispus (S. crispus) is a herbal medicinal plant that is indigenous in Madagascar and the Malay Archipelago. Based on the antifungal activity observed the S. crispus extract was used to determine the minimum inhibitory concentration (MIC).The MIC was determined by using amended PDA media containing several S. crispus extract concentrations 13: 10, 5, 2.5, 1.25 and 0 mg mL - 1.. About 100 L of fungi inoculum was pipetted into each prepared PDA media for MIC test and spread by using sterile cotton . Recent studies by Singapore researchers had found this super herb to have anticancer effect against 7 types of cancer - colon, breast, ovarian, uterine, cervical, liver and leukaemia. Because in this plant there is potassium is very good for kidney health.

Strobilanthes crispus is a flowering shrub that grows up to 2 meters tall, usually found wild near riverbanks, abandoned fields or in scrublands. leaves, when consumed will compete with cholesterol for absorption in the digestive system. The leaves of Strobilanthes crispus (S. crispus) which is native to the regions of Madagascar to the Malay Archipelago, are used in folk medicine for their antidiabetic, diuretic, anticancer and blood pressure lowering properties. The ethnopharmacological value of this plant, such as the development of nutraceutical S. crispus herbal tea (fermented . In this study, we set out to . Aim of the study: KEY FACTS. 2. The ethnopharmacological value of this plant, such as the development of nutraceutical S. crispus herbal tea (fermented . We showed that a bioactive sub-fraction of S. crispus leaves (SCS) induced cell cycle arrest and apoptosis of human breast cancer cell lines. Herbs and herb mixtures have been used as a growth promotant in livestock and aquaculture production. S. crispus is an ethnomedicinal plant with high antioxidant content and is indicated in the treatment of diabetes, cancer, and hypertension. Many studies need to be done to promote the usage and application of these native plants.

KW - Process synthesis. This study aimed to evaluate the functional potential of cookie enhanced with Strobilanthes crispus (SC) and to evaluate its physicochemical and organoleptic properties . The plant possesses high vitamin and mineral content as well as phytochemicalslike phenols, catechins, tannins, and flavonoidsthat are known to have therapeutic effects. Among the medicinal plants, one of the commonly found plants in tropical countries is Strobilanthes crispa Blume.